Next step towards functional precision medicine in neuro-oncology

Weiss T, Lee S, Snijder B, Weller M.

Neuro Oncology. 2025 Jan 12;27(1):5-6. doi: 10.1093/neuonc/noae233

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Molecular and functional landscape of malignant serous effusions for precision oncology

Wegmann R, Bankel L, Festl Y, Lau K, Lee S, Arnold F, Cappelletti V, Fehr A, Picotti P, Dedes KJ, Franzen D, Lenggenhager D, Bode PK, Zoche M, Moch H, Britschgi C, Snijder B.

Nature Communications. 2024 Oct 2;15(1):8544. doi: 10.1038/s41467-024-52694-8

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Cellular architecture shapes the naïve T cell response

Hale BD, Severin Y, Graebnitz F, Stark D, Guignard D, Mena J, Festl Y, Lee S, Hanimann J, Zangger NS, Meier M, Goslings D, Lamprecht O, Frey BM, Oxenius A, Snijder B.

Science. 2024 Jun 7;384(6700):eadh8697. doi: 10.1126/science.adh8967

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Targeting the Siglec-sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma

Schmassmann P, Roux J, Buck A, Tatari N, Hogan S, Wang J, Mantuano NR, Wieboldt R, Lee S, Snijder B, Kaymak D, Martins TA, Ritz M, Shekarian T, McDaid M, Weller M, Weiss T, Laeubli H, Hutter G.

Science Translational Medicine. 2023 Jul 19; 15 (705). doi: 10.1126/scitranslmed.adf5302

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Self-supervised vision transformers accurately decode cellular state heterogeneity

Pfaendler R*, Hanimann J*, Lee S, Snijder B.

bioRxiv (pre-print). 2023 Jan 18. doi: 10.1101/2023.01.16.524226

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Multifunctional mRNA-based CAR T cells display promising antitumor activity against glioblastoma

Meister H, Look T, Roth P, Pascolo S Sahin U, Lee S, Hale BD, Snijder B, Regli L, Ravi VM, Heiland DH, Sentman CL, Weller M, Weiss T.

Clinical Cancer Research. 2022 Nov 01, 28(21):4747-4756, doi: 10.1158/1078-0432.ccr-21-4384

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Allosteric antagonist modulation of TRPV2 by piperlongumine impairs glioblastoma progression

Conde, J, Pumroy RA, Baker C, Rodrigues T, Guerreiro A, Sousa BB, Marques MC, de Almeida B P, Lee S, Leites EP, Picard D, Samanta A, Vaz SH, Sieglitz F, Langini M, Remke M, Roque R, Weiss T, Weller M, … , Bernardes G.

ACS Central Science. 2021 May 26; 7(5):868-881. doi: 10.1021/acscentsci.1c00070

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Kinase interaction network expands functional and disease roles of human kinases

Buljan M, Ciuffa R, van Drogen A, Vichalkovski A, Mehnert M, Rosenberger G, Lee S, Varjosalo M, Pernas LE, Spegg V, Snijder B, Aebersold R, Gstaiger M.

Molecular Cell. 2020 Aug 6;79(3):504-520.e9. doi: 10.1016/j.molcel.2020.07.001

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Replacing reprogramming factors with antibodies selected from combinatorial antibody libraries

Blanchard JW*, Xie J*, El-Mecharrafie N, Gross S, Lee S, Lerner RA, Baldwin KK.

Nature Biotechnology. 2017 Sep 11; 35: 960–968 doi: 10.1038/nbt.3963

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Terminal axon branching is regulated by the LKB1-NUAK1 kinase pathway via presynaptic mitochondrial capture

Courchet J*, Lewis TL Jr*, Lee S, Courchet V, Liou DY, Aizawa S, Polleux F.

Cell. 2013 Jun 20; 153(7):1510-25. doi: 10.1016/j.cell.2013.05.021